Roadway pavement surface distress information is critical for effective pavement asset management, and subsequently, transportation management agencies at all levels (i.e., federal, state, and local) dedicate a large amount of time and money to routinely evaluate pavement surface distress conditions as the core of their asset management programs.Ho
In the course of infection and intense endotoxemia processes, induction of a catabolic state leading to weight loss is observed in mice and humans.However, the late effects of acute inflammation on energy homeostasis, regulation of body weight and glucose metabolism are yet to be elucidated.Here, we addressed whether serial intense endotoxemia, cha
Glucocorticoid (GC) hormones are significant regulators of homeostasis.The physiological effects of GCs critically depend on the time of exposure (short vs.long) as well as on their circulating levels (baseline vs.stress-induced).Previous experiments, in which chronic and high elevation of GC levels was induced, indicate that GCs impair both the ac
Following viral infection, viral antigens bind specifically to receptors on the surface of lymphocytes thereby activating adaptive immunity in the host.An epitope, the smallest structural and functional unit of an antigen, binds specifically to an antibody or antigen receptor, to serve as key sites for the activation of adaptive immunity.The comple